Babesiosis na nkịta: ọgwụgwọ

 Maka ọgwụgwọ nke nkịta na-ata ahụhụ site na babesiosis, a nwalere ọnụ ọgụgụ dị ukwuu nke ọgwụ dị iche iche na nsonaazụ dị iche iche. 

Otú ọ dị, ihe mmepụta diamidine eji agwọ ọrịa babesiosis canine (berenil, batryzin, verbiben, azidin, wdg) nwere ngwa ngwa bara uru. Ihe na-arụ ọrụ nke ọgwụ ndị a bụ diminazene aceturate. Azidine nwere ihe na-arụ ọrụ 100%. A na-emepụta Berenil n'ụdị granules, 23,6 g nke nwere 10,5 g nke ihe na-arụ ọrụ. A na-emepụta Batrizin n'ụdị granules, 10,5 g nke nwere 4,66 g nke ihe na-arụ ọrụ. A na-emepụta Veriben n'ụdị granules, 2,36 g nke nwere 1,05 g nke ihe na-arụ ọrụ. Azidine, berenil na batryzine so na otu "B" n'ihe gbasara nsi. Ọgwụ kacha anabatara maka ụmụ oke bụ 40 mg / kg, maka oke bekee - 25-30 mg / kg, nkịta, ehi na ịnyịnya - 10 mg / n'arọ. Ọgwụ ndị ahụ enweghị mmetụta mkpokọta akpọpụtara, mana na oke doses ha na-ebute nsị, nke ọrịa ji arụ ọrụ nke sistemu ụjọ nke etiti: tonic convulsions, ataxia, na mgbe ụfọdụ vomiting. Veriben bụ nke ogige ndị na-egbu egbu maka anụmanụ nwere ọbara ọkụ. Ọgwụ ahụ na-agbakọta tumadi na imeju na akụrụ, na obere ntakịrị na ụbụrụ ma na-esi na ya pụta na mmamịrị. Omume nke ọgwụ na-adabere na mgbochi nke aerobic glycolysis na DNA njikọ na pathogenic protozoa, mmetụta na mma Ọdịdị na ọrụ nke cell membranes. Ọrịa nje na-eguzogide n'otu n'otu na berenil bụ ihe dị mkpa na-adị ndụ n'otu n'otu. Mwepụta nke abụọ nke diamidine, nke dị irè ma megide B. canis, na ụdị ọrịa ndị ọzọ - pentamidine, na-eji na dose nke 16,5 mg / kg ugboro abụọ na oge kwa ụbọchị. Site n'iji ya eme ihe, mmetụta ndị dị ka mgbu na saịtị injection, tachycardia, ọgbụgbọ na vomiting ga-ekwe omume. Ọgwụ dị oke irè megide B. canis bụ imidocarb (mwepụta nke carbanilide) eji na dose nke 5 mg / kg. Dị ka ụfọdụ ndị edemede si kwuo, berenyl na azidine na-ekpochapụ ahụ anụmanụ site na piroplasmids ma gbochie babesiosis mgbe a na-enye ya 5-10 na ọbụna ụbọchị 17 tupu ọrịa. Dị ka DA si kwuo Strashnova (1975), berenil na dose nke 7 mg / kg nke arọ ahụ na-egbochi ọrịa nke nkịta nwere pathogen B. canis n'ime ụbọchị 15. Agbanyeghị, nchịkwa nke berenyl maka ebumnuche prophylactic n'otu oge na ọbara mbuso agha emeghị ka ahụ nke nkịta si na B. canis, ma, ka o sina dị, mmụba nke pathogen n'ime ọbara na-ebelata nke ukwuu. Iji belata mmetụta nke pathological n'ihi ọrụ dị mkpa nke nje nje na ọnụ ọgụgụ ha nwụrụ mgbe nchịkwa nke ọgwụ mgbochi ụmụaka, yana iji belata mmetụta nsị nke ọgwụ protistocidal, a ga-eji ọgwụgwọ mgbaàmà dị iche iche mee ihe. Maka imeziwanye ọrụ obi, a na-eji nkwadebe obi dị iche iche. Ọtụtụ mgbe, a na-eji sulfocamphocaine n'ụdị ngwọta 10% subcutaneously ma ọ bụ intramuscularly na dose nke 1,0 ml kwa kilogram 20 nke nkịta dị ndụ. A na-enye ọgwụ ahụ ugboro 1-2 n'oge usoro ọgwụgwọ dum. A na-ejikwa ọgwụgwọ obi ndị ọzọ (riboxin, cordiamin, camphor). Iji belata mmịnị n'ozuzu, a na-eji gamavit ọgwụ eme ihe, nke nwere ngwakọta physiologically dabara adaba nke amino acid 20, vitamin 17, iberibe nucleic acid, ihe ndị na-achọpụta ihe, yana wepụ placental na immunostimulant (sodium nucleinate). Isi ihe na-egosi maka iji gamavit bụ ihe onwunwe ya dị ka ihe na-egbu egbu, nke na-eme ka nkwụsịtụ na mwepụ nke ngwaahịa ire ere na-egbu egbu, ma na-eme ka ọrụ ndị ahụ na-akpaghasị anya n'ihi ikpughe ha. Gamavit na-enye aka na mweghachi nke ọrụ hematopoietic na-adịghị mma na babesiosis. ₉) na L-glutamic acid, na-etinye aka n'ịkwagide hematopoiesis. Ekwesịrị inye ọgwụ ahụ na subcutaneously na dose nke 0,1 ml / n'arọ nke ịdị arọ ahụ maka ụbọchị 5-7. Ọtụtụ mgbe, edema nke akụkụ ahụ dị iche iche na nkịta na hemorrhages na akpụkpọ anụ mucous nwere ihe jikọrọ ya na ọ bụ n'ihi mmụba nke porosity vaskụla n'ihi ikpughe na nsị. Iji weghachi iguzosi ike n'ezi ihe ma gbochie mmebi nke mgbidi vaskụla, a na-eji etamsylate (dicinone) mee ihe n'ụdị 12,5% ngwọta intramuscularly. A na-enye ọgwụ ahụ na dose 1,0 ml kwa kilogram 20 nke ịdị arọ ahụ otu ugboro n'ụbọchị maka ụbọchị 2-3 mbụ nke ọgwụgwọ. Ihe omume meningeal edebanyere aha na ụfọdụ nkịta nwere ike ịbụ n'ihi mmepe nke microflora ohere n'ihi mbelata nke nguzogide anụ ahụ na-arịa ọrịa. Ya mere, iji gbochie ihe mgbagwoju anya nke mgbaàmà a, ọ dị mkpa iji ọgwụ nje. Dabere na nke a, a ga-etinye injections nke nnu sodium benzylpenicillin na usoro ọgwụgwọ maka babesiosis iji gbochie ihe omume meningeal na nkịta. A na-enye ọgwụ ahụ intramuscularly na dose nke 10-15 puku nkeji kwa kilogram nke ịdị arọ ahụ kwa awa 6, na-amalite site na mbụ dose nke anụmanụ, n'oge usoro ọgwụgwọ. A na-eji antihistamines na corticosteroids (dexamethasone, prednisolone) mee ihe iji belata nzaghachi mkpali n'ozuzu ya. A maara na iji ogologo oge nke corticosteroids nwere ike ime ka mmebi nke mmiri-sodium metabolism n'ime ahụ ma ọ bụ na-eduga na mgbochi nke ọrụ nke adrenal cortex. Ya mere, iji zere ihe ndị a, n'ime ụbọchị abụọ gara aga, a na-enye ọgwụ ahụ na obere doses. Iji nọgide na-arụ ọrụ imeju na nkịta na-arịa ọrịa, a na-ejikwa Essentiale forte na dose nke 3-5 ml maka anụmanụ ọ bụla na intravenously maka ụbọchị 5-7.

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